Olesoxime Inhibits Cardioplegia-Induced Ischemia/Reperfusion Injury. A Study in Langendorff-Perfused Rabbit Hearts

Objective: During cardioplegia, which is often used in cardiac surgery, the heart is subjected to global ischemia/reperfusion injury, which can result in a post-operative impairment of cardiac function. Mitochondria permeability transition pores (MPTP) play a key role in cardiomyocyte survival after...

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Bibliographic Details
Main Authors: Aida Salameh, Maren Keller, Ingo Dähnert, Stefan Dhein
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Physiology
Subjects:
ATP
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00324/full