Validation of glypican-3-specific scFv isolated from paired display/secretory yeast display library

<p>Abstract</p> <p>Background</p> <p>Glypican-3 (GPC3) is a heparan-sulfate proteoglycan frequently expressed on the cell membrane of malignant hepatocytes in hepatocellular carcinoma. The capacity for screening potential antibodies in vitro using human hepatocellular l...

Full description

Bibliographic Details
Main Authors: Li Yonghai, Siegel Donald L, Scholler Nathalie, Kaplan David E
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/12/23