Characterization of lamin mutation phenotypes in Drosophila and comparison to human laminopathies.

Lamins are intermediate filament proteins that make up the nuclear lamina, a matrix underlying the nuclear membrane in all metazoan cells that is important for nuclear form and function. Vertebrate A-type lamins are expressed in differentiating cells, while B-type lamins are expressed ubiquitously....

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Bibliographic Details
Main Authors: Andrés Muñoz-Alarcón, Maja Pavlovic, Jasmine Wismar, Bertram Schmitt, Maria Eriksson, Per Kylsten, Mitchell S Dushay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1885830?pdf=render