Interactome and reciprocal activation of pathways in topical mesenchymal stem cells and the recipient cerebral cortex following traumatic brain injury

Abstract In this study, GFP-MSCs were topically applied to the surface of cerebral cortex within 1 hour of experimental TBI. No treatment was given to the control group. Three days after topical application, the MSCs homed to the injured parenchyma and improved the neurological function. Topical MSC...

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Bibliographic Details
Main Authors: Ping K. Lam, Kevin K. W. Wang, Anthony W. I. Lo, Cindy S. W. Tong, Don W. C. Ching, Kenneth Wong, Zhihui Yang, Themis Kong, Kin K. Y. Lo, Richard K. W. Choy, Paul B. S. Lai, George K. C. Wong, Wai S. Poon
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01772-7