The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation

Summary: Palmitoylation is a reversible post-translational lipid modification that facilitates vesicular transport and subcellular localization of modified proteins. This process is catalyzed by ZDHHC enzymes that are implicated in several neurological and neurodevelopmental disorders. Loss-of-funct...

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Main Authors: Jordan J. Shimell, Bhavin S. Shah, Stuart M. Cain, Samrat Thouta, Naila Kuhlmann, Igor Tatarnikov, D. Blair Jovellar, G. Stefano Brigidi, Jennifer Kass, Austen J. Milnerwood, Terrance P. Snutch, Shernaz X. Bamji
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719313798