Analysis of SOX2-Regulated Transcriptome in Glioma Stem Cells.

INTRODUCTION:Glioblastoma is the most malignant brain tumor in adults and is associated with poor survival despite multimodal treatments. Glioma stem-like cells (GSCs) are cells functionally defined by their self-renewal potential and the ability to reconstitute the original tumor upon orthotopic im...

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Main Authors: Arlet M Acanda de la Rocha, Hernando López-Bertoni, Elizabeth Guruceaga, Marisol González-Huarriz, Naiara Martínez-Vélez, Enric Xipell, Juan Fueyo, Candelaria Gomez-Manzano, Marta M Alonso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5036841?pdf=render