Angiopoietin/Tie2 pathway mediates type 2 diabetes induced vascular damage after cerebral stroke
We investigated the changes and the molecular mechanisms of cerebral vascular damage after stroke in type-2 diabetic (T2DM) mice. Adult male db/db T2DM and wild-type (WT) mice were subjected to transient middle cerebral artery occlusion (MCAo) and sacrificed 24 hours after MCAo. T2DM-mice exhibited...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2011-07-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996111001227 |