Bradykinin enhances membrane electrical activity of pancreatic beta cells in the presence of low glucose concentrations
In most of cells bradykinin (BK) induces intracellular calcium mobilization. In pancreatic beta cells intracellular calcium is a major signal for insulin secretion. In these cells, glucose metabolism yields intracellular ATP which blocks membrane potassium channels. The membrane depolarizes, voltage...
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Divulgação Científica
2000-09-01
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| Series: | Brazilian Journal of Medical and Biological Research |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000900016 |