C. elegans agrin is expressed in pharynx, IL1 neurons and distal tip cells and does not genetically interact with genes involved in synaptogenesis or muscle function.

Agrin is a basement membrane protein crucial for development and maintenance of the neuromuscular junction in vertebrates. The C. elegans genome harbors a putative agrin gene agr-1. We have cloned the corresponding cDNA to determine the primary structure of the protein and expressed its recombinant...

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Bibliographic Details
Main Authors: Ana Hrus, Gordon Lau, Harald Hutter, Susanne Schenk, Jacqueline Ferralli, Marianne Brown-Luedi, Ruth Chiquet-Ehrismann, Stefano Canevascini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1939731?pdf=render