Structural characterization of NrnC identifies unifying features of dinucleotidases

RNA degradation is fundamental for cellular homeostasis. The process is carried out by various classes of endolytic and exolytic enzymes that together degrade an RNA polymer to mono-ribonucleotides. Within the exoribonucleases, nano-RNases play a unique role as they act on the smallest breakdown pro...

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Bibliographic Details
Main Authors: Justin D Lormand, Soo-Kyoung Kim, George A Walters-Marrah, Bryce A Brownfield, J Christopher Fromme, Wade C Winkler, Jonathan R Goodson, Vincent T Lee, Holger Sondermann
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/70146