Dynamic Duo—The Salmonella Cytolethal Distending Toxin Combines ADP-Ribosyltransferase and Nuclease Activities in a Novel Form of the Cytolethal Distending Toxin

The cytolethal distending toxin (CDT) is a well characterized bacterial genotoxin encoded by several Gram-negative bacteria, including Salmonella enterica (S. enterica). The CDT produced by Salmonella (S-CDT) differs from the CDT produced by other bacteria, as it utilizes subunits with homology to t...

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Bibliographic Details
Main Authors: Rachel Miller, Martin Wiedmann
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/8/5/121