The protective role of endogenous nitric oxide donor (L-arginine) in cisplatin-induced nephrotoxicity: Gender related differences in rat model

The protective role of endogenous nitric oxide donor (L-arginine) in cisplatin-induced nephrotoxicity: Gender related differences in rat model

Background: Cisplatin (CP) as a potential drug for solid tumors produces nephrotoxicity and disturbs endothelial function. CP induced nephrotoxicity may be gender related. Nitric oxide plays a pivotal role in endothelial function and L-arginine as endogenous NO donor promotes endothelial function. T...

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Bibliographic Details
Main Authors: Fatemeh Eshraghi-Jazi, Mehdi Nematbakhsh, Hamid Nasri, Ardeshir Talebi, Maryam Haghighi, Zahra Pezeshki, Tahereh Safari, Farzaneh Ashrafi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Journal of Research in Medical Sciences
Subjects:
Gender
L-arginine
Cisplatin
Nephrotoxicity
Rat
Online Access:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2011;volume=16;issue=11;spage=1389;epage=1396;aulast=Eshraghi-Jazi

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http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2011;volume=16;issue=11;spage=1389;epage=1396;aulast=Eshraghi-Jazi

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