Design and cloning strategies for constructing shRNA expression vectors
<p>Abstract</p> <p>Background</p> <p>Short hairpin RNA (shRNA) encoded within an expression vector has proven an effective means of harnessing the RNA interference (RNAi) pathway in mammalian cells. A survey of the literature revealed that shRNA vector construction can...
Main Authors: | McIntyre Glen J, Fanning Gregory C |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-01-01
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Series: | BMC Biotechnology |
Online Access: | http://www.biomedcentral.com/1472-6750/6/1 |
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