Design and cloning strategies for constructing shRNA expression vectors

<p>Abstract</p> <p>Background</p> <p>Short hairpin RNA (shRNA) encoded within an expression vector has proven an effective means of harnessing the RNA interference (RNAi) pathway in mammalian cells. A survey of the literature revealed that shRNA vector construction can...

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Bibliographic Details
Main Authors: McIntyre Glen J, Fanning Gregory C
Format: Article
Language:English
Published: BMC 2006-01-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/6/1