Programmed cellular necrosis mediated by the pore-forming alpha-toxin from Clostridium septicum.

Programmed necrosis is a mechanism of cell death that has been described for neuronal excitotoxicity and ischemia/reperfusion injury, but has not been extensively studied in the context of exposure to bacterial exotoxins. The alpha-toxin of Clostridium septicum is a beta-barrel pore-forming toxin an...

Full description

Bibliographic Details
Main Authors: Catherine L Kennedy, Danielle J Smith, Dena Lyras, Anjana Chakravorty, Julian I Rood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19609357/pdf/?tool=EBI