Sex Differences in Autophagy Contribute to Female Vulnerability in Alzheimer's Disease

Alzheimer's disease (AD) is the most common form of dementia, with over 5. 4 million cases in the US alone (Alzheimer's Association, 2016). Clinically, AD is defined by the presence of plaques composed of Aβ and neurofibrillary pathology composed of the microtubule associated protein tau....

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Bibliographic Details
Main Author: Erin E. Congdon
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Neuroscience
Subjects:
sex
tau
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00372/full