Reduced gamma oscillations in a mouse model of intellectual disability: a role for impaired repetitive neurotransmission?

Reduced gamma oscillations in a mouse model of intellectual disability: a role for impaired repetitive neurotransmission?

Intellectual disability affects 2-3% of the population; mutations of the X-chromosome are a major cause of moderate to severe cases. The link between the molecular consequences of the mutation and impaired cognitive function remains unclear. Loss of function mutations of oligophrenin-1 (OPHN1) disru...

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Bibliographic Details
Main Authors: Andrew D Powell, Pierre-Philippe Saintot, Kalbinder K Gill, Ashtami Bharathan, S Caroline Buck, Gareth Morris, Premysl Jiruska, John G R Jefferys
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4011727?pdf=render

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http://europepmc.org/articles/PMC4011727?pdf=render

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