The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants.

The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants.

Pink1 is a mitochondrial kinase involved in Parkinson's disease, and loss of Pink1 function affects mitochondrial morphology via a pathway involving Parkin and components of the mitochondrial remodeling machinery. Pink1 loss also affects the enzymatic activity of isolated Complex I of the elect...

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Bibliographic Details
Main Authors: Sven Vilain, Giovanni Esposito, Dominik Haddad, Onno Schaap, Mariya P Dobreva, Melissa Vos, Stefanie Van Meensel, Vanessa A Morais, Bart De Strooper, Patrik Verstreken
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3252300?pdf=render

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http://europepmc.org/articles/PMC3252300?pdf=render

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