Activation of G Proteins by Guanine Nucleotide Exchange Factors Relies on GTPase Activity.

G proteins are an important family of signalling molecules controlled by guanine nucleotide exchange and GTPase activity in what is commonly called an 'activation/inactivation cycle'. The molecular mechanism by which guanine nucleotide exchange factors (GEFs) catalyse the activation of mon...

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Bibliographic Details
Main Authors: Rob J Stanley, Geraint M H Thomas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4795700?pdf=render