Comparison of results from different imputation techniques for missing data from an anti-obesity drug trial.

<h4>Background</h4>In randomised trials of medical interventions, the most reliable analysis follows the intention-to-treat (ITT) principle. However, the ITT analysis requires that missing outcome data have to be imputed. Different imputation techniques may give different results and som...

Full description

Bibliographic Details
Main Authors: Anders W Jørgensen, Lars H Lundstrøm, Jørn Wetterslev, Arne Astrup, Peter C Gøtzsche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0111964