Amyloid precursor protein, lipofuscin accumulation and expression of autophagy markers in aged bovine brain

Amyloid precursor protein, lipofuscin accumulation and expression of autophagy markers in aged bovine brain

Abstract Background Autophagy is a highly regulated process involving the bulk degradation of cytoplasmic macromolecules and organelles in mammalian cells via the lysosomal system. Dysregulation of autophagy is implicated in the pathogenesis of many neurodegenerative diseases and integrity of the au...

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Bibliographic Details
Main Authors: D. De Biase, A. Costagliola, T.B. Pagano, G. Piegari, S. Wojcik, J. Dziewiątkowski, E. Grieco, G. Mattace Raso, V. Russo, S. Papparella, O. Paciello
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Veterinary Research
Subjects:
Autophagy
Brain
Neuropathology
Ageing
Bovine
Online Access:http://link.springer.com/article/10.1186/s12917-017-1028-1

Internet

http://link.springer.com/article/10.1186/s12917-017-1028-1

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