AAV9-Retro mediates efficient transduction with axon terminal absorption and blood–brain barrier transportation

AAV9-Retro mediates efficient transduction with axon terminal absorption and blood–brain barrier transportation

Abstract Recombinant adeno-associated viruses (rAAVs), particularly those that permit efficient gene transfer to neurons from axonal terminals or across the blood–brain barrier, are useful vehicles for structural and functional studies of the neural circuit and for the treatment of many gene-deficie...

Full description

Bibliographic Details
Main Authors: Kunzhang Lin, Xin Zhong, Lei Li, Min Ying, Tian Yang, Zhijian Zhang, Xiaobin He, Fuqiang Xu
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Molecular Brain
Subjects:
Adeno-associated viruses
Retrogradely
AAV9-retro
Across the blood–brain barrier
Neural circuits
Online Access:http://link.springer.com/article/10.1186/s13041-020-00679-1

Internet

http://link.springer.com/article/10.1186/s13041-020-00679-1

Similar Items