Rapamycin inhibits pathogen transmission in mosquitoes by promoting immune activation.

Repeated blood meals provide essential nutrients for mosquito egg development and routes for pathogen transmission. The target of rapamycin, the TOR pathway, is essential for vitellogenesis. However, its influence on pathogen transmission remains to be elucidated. Here, we show that rapamycin, an in...

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Bibliographic Details
Main Authors: Yuebiao Feng, Lu Chen, Li Gao, Li Dong, Han Wen, Xiumei Song, Fang Luo, Gong Cheng, Jingwen Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009353