MALAT1 knockdown inhibits proliferation and enhances cytarabine chemosensitivity by upregulating miR-96 in acute myeloid leukemia cells

MALAT1 knockdown inhibits proliferation and enhances cytarabine chemosensitivity by upregulating miR-96 in acute myeloid leukemia cells

Drug resistance remains a major cause of relapse and therapeutic failure in acute myeloid leukemia (AML). Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been documented to act as an oncogene and is frequently highly expressed in human cancers including AML. However, the function...

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Bibliographic Details
Main Authors: Ning Hu, Li Chen, Chao Wang, Hongmian Zhao
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
MALAT1
miR-96
Proliferation
Ara-C sensitivity
Acute myeloid leukemia
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218382866

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http://www.sciencedirect.com/science/article/pii/S0753332218382866

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