High IL2RA mRNA expression is an independent adverse prognostic biomarker in core binding factor and intermediate-risk acute myeloid leukemia

High IL2RA mRNA expression is an independent adverse prognostic biomarker in core binding factor and intermediate-risk acute myeloid leukemia

Abstract Background Elevated protein expressions of CD markers such as IL2RA/CD25, CXCR4/CD184, CD34 and CD56 are associated with adverse prognosis in acute myeloid leukemia (AML). However, the prognostic value of mRNA expressions of these CD markers in AML remains unclear. Through our pilot evaluat...

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Bibliographic Details
Main Authors: Wen Du, Jing He, Wei Zhou, Simin Shu, Juan Li, Wei Liu, Yun Deng, Cong Lu, Shengyan Lin, Yaokun Ma, Yanli He, Jine Zheng, Jiang Zhu, Lijuan Bai, Xiaoqing Li, Junxia Yao, Dan Hu, Shengqing Gu, Huiyu Li, Anyuan Guo, Shiang Huang, Xiaolan Feng, Dong Hu
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Translational Medicine
Subjects:
Acute myeloid leukemia
Prognosis
IL2RA
mRNA expression
Core binding factor AML
Intermediate-risk AML
Online Access:http://link.springer.com/article/10.1186/s12967-019-1926-z

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http://link.springer.com/article/10.1186/s12967-019-1926-z

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