Neuroprotection and neuroregeneration of retinal ganglion cells after intravitreal carbon monoxide release.

Retinal ischemia induces apoptosis leading to neurodegeneration and vision impairment. Carbon monoxide (CO) in gaseous form showed cell-protective and anti-inflammatory effects after retinal ischemia-reperfusion-injury (IRI). These effects were also demonstrated for the intravenously administered CO...

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Bibliographic Details
Main Authors: Julia Stifter, Felix Ulbrich, Ulrich Goebel, Daniel Böhringer, Wolf Alexander Lagrèze, Julia Biermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5703485?pdf=render