Cooperative Interactions of HER-2, HPV-16 Oncoproteins in the Malignant Transformation of Human Mammary Epithelial Cells
To better underst, the mechanisms of transformation by the oncogene HER-2, we transduced the human mammary epithelial (HME) cell line MCF-10A with HER-2, developed a cell line that appeared to moderately overexpress HER-2. These MCF-10HER-2 cells were unable to grow in the absence of epidermal grow...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2005-08-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558605801113 |