Cooperative Interactions of HER-2, HPV-16 Oncoproteins in the Malignant Transformation of Human Mammary Epithelial Cells

To better underst, the mechanisms of transformation by the oncogene HER-2, we transduced the human mammary epithelial (HME) cell line MCF-10A with HER-2, developed a cell line that appeared to moderately overexpress HER-2. These MCF-10HER-2 cells were unable to grow in the absence of epidermal grow...

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Bibliographic Details
Main Authors: Kathleen M. Woods Ignatoski, Michele L. Dziubinski, Cheryl Ammerman, Stephen P. Ethier
Format: Article
Language:English
Published: Elsevier 2005-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605801113