Opioid users show worse baseline knee osteoarthritis and faster progression of degenerative changes: a retrospective case-control study based on data from the Osteoarthritis Initiative (OAI)

Opioid users show worse baseline knee osteoarthritis and faster progression of degenerative changes: a retrospective case-control study based on data from the Osteoarthritis Initiative (OAI)

Abstract Background Opioids are frequently prescribed for pain control in knee osteoarthritis patients, despite recommendations by current guidelines. Previous studies have investigated the chondrotoxicity of different opioid subtypes. However, the impact opioids may have on progression of osteoarth...

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Bibliographic Details
Main Authors: Jannis Bodden, Gabby B. Joseph, Silvia Schirò, John A. Lynch, Nancy E. Lane, Charles E. McCulloch, Michael C. Nevitt, Thomas M. Link
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Arthritis Research & Therapy
Subjects:
Osteoarthritis
Knee
Magnetic resonance imaging
Opioids
Pain
Osteoarthritis Initiative
Online Access:https://doi.org/10.1186/s13075-021-02524-9

Internet

https://doi.org/10.1186/s13075-021-02524-9

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