Synthesis and biological activity of new 18β-glycyrrhetinic acid derivatives

In an attempt to find out new, potent and safe anti-inflammatory molecules and as a contribution in the chemistry of triterpenes, a series of 18β-glycyrrhetinic acid (GTA) derivatives (4a–j, 5a–e, 7–9, 11–13) were synthesized and evaluated as anti-inflammatory agents using carrageenan induced rat pa...

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Bibliographic Details
Main Authors: Mohamed O. Radwan, Mohamed A.H. Ismail, Sahar El-Mekkawy, Nasser S.M. Ismail, Atef G. Hanna
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535213001986