Small dense HDLs display potent vasorelaxing activity, reflecting their elevated content of sphingosine-1-phosphate

Small dense HDLs display potent vasorelaxing activity, reflecting their elevated content of sphingosine-1-phosphate

The functional heterogeneity of HDL is attributed to its diverse bioactive components. We evaluated whether the vasodilatory effects of HDL differed across HDL subpopulations, reflecting their distinct molecular composition. The capacity of five major HDL subfractions to counteract the inhibitory ef...

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Bibliographic Details
Main Authors: Laurence Perségol, Maryam Darabi, Carolane Dauteuille, Marie Lhomme, Sandrine Chantepie, Kerry-Anne Rye, Patrice Therond, M. John Chapman, Robert Salvayre, Anne Nègre-Salvayre, Philippe Lesnik, Serge Monier, Anatol Kontush
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
vasodilation
oxidized low density lipoprotein
endothelium
nitric oxide
high density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339298

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http://www.sciencedirect.com/science/article/pii/S0022227520339298

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