Development of Depotentiation in Adult-Born Dentate Granule Cells

Activity-dependent synaptic plasticity, i.e., long-term potentiation (LTP), long-term depression (LTD) and LTP reversal, is generally thought to make up the cellular mechanism underlying learning and memory in the mature brain, in which N-methyl-D-aspartate subtype of glutamate (NMDA) receptors and...

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Bibliographic Details
Main Authors: Xiaoqing Tao, Ning Sun, Yangling Mu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
LTP
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00236/full