Neurons Derived From Patient-Specific Induced Pluripotent Stem Cells: a Promising Strategy Towards Developing Novel Pharmacotherapies for Autism Spectrum Disorders

Neurons Derived From Patient-Specific Induced Pluripotent Stem Cells: a Promising Strategy Towards Developing Novel Pharmacotherapies for Autism Spectrum Disorders

Bibliographic Details
Main Authors:	Ryan Mokhtari, Herbert M. Lachman
Format:	Article
Language:	English
Published:	Elsevier 2016-07-01
Series:	EBioMedicine
Subjects:	Induced pluripotent Neuron Screening Shank3
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396416302900

Similar Items

Current State-of-the-Art and Unresolved Problems in Using Human Induced Pluripotent Stem Cell-Derived Dopamine Neurons for Parkinson’s Disease Drug Development
by: S. A. Antonov, et al.
Published: (2021-03-01)

Human Pluripotent Stem Cell-derived Cortical Neurons for High Throughput Medication Screening in Autism: A Proof of Concept Study in SHANK3 Haploinsufficiency Syndrome
by: Hélène Darville, et al.
Published: (2016-07-01)

Characterization of Induced Pluripotent Stem Cell-derived Human Serotonergic Neurons
by: Lining Cao, et al.
Published: (2017-05-01)

Prospects for Modeling Abnormal Neuronal Function in Schizophrenia Using Human Induced Pluripotent Stem Cells
by: Iya Prytkova, et al.
Published: (2017-11-01)

Comparative Neuronal Differentiation of Self-Renewing Neural Progenitor Cell Lines Obtained from Human Induced Pluripotent Stem Cells
by: Chiara eVerpelli, et al.
Published: (2013-10-01)

Differentiation and Characterization of Dopaminergic Neurons From Baboon Induced Pluripotent Stem Cells
by: Douglas A. Grow, et al.
Published: (2016-09-01)

Pluripotent stem cells induced to neural lineages and neural tissues.
by: Yannick eMartinez, et al.
Published: (2012-03-01)

Pluripotency of induced pluripotent stem cells
by: Kang Lan, et al.
Published: (2012-02-01)

Restoring Motor Neurons in Spinal Cord Injury With Induced Pluripotent Stem Cells
by: Matthew Trawczynski, et al.
Published: (2019-08-01)

Human stem cell-based models for studying autism spectrum disorder-related neuronal dysfunction
by: Arquimedes Cheffer, et al.
Published: (2020-12-01)

Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells
by: Jesse Barnes, et al.
Published: (2018-08-01)

Uncovering the Functional Link Between SHANK3 Deletions and Deficiency in Neurodevelopment Using iPSC-Derived Human Neurons
by: Guanqun Huang, et al.
Published: (2019-03-01)

Utilisation des cellules souches pluripotentes pour la recherche et la validation de composés thérapeutiques pour les formes génétiques d'autisme liées à SHANK3
by: Darville, Hélène
Published: (2015)

Isolation and Culture of Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoid Cells
by: Arzua, T., et al.
Published: (2022)

High-throughput screen for compounds that modulate neurite growth of human induced pluripotent stem cell-derived neurons
by: Sean P. Sherman, et al.
Published: (2018-02-01)

Rapid generation of sub-type, region-specific neurons and neural networks from human pluripotent stem cell-derived neurospheres
by: Aynun N. Begum, et al.
Published: (2015-11-01)

Systemic administration of valproic acid and zonisamide promotes the survival and differentiation of induced pluripotent stem cell–derived dopaminergic neurons
by: Tatsuya eYoshikawa, et al.
Published: (2013-02-01)

Generation of striatal neurons from human induced pluripotent stem cells by controlling extrinsic signals with small molecules
by: Naoya Amimoto, et al.
Published: (2021-08-01)

Using induced pluripotent stem cells derived neurons to model brain diseases
by: Cindy E McKinney
Published: (2017-01-01)

The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation
by: Monique Bax, et al.
Published: (2019-06-01)

Patient-Specific Induced Pluripotent Stem Cell Models of Parkinson’s Disease
by: Liao, Mei-Chih
Published: (2014)

Disease-specific pluripotent stem cells
by: Hoon-Chul Kang
Published: (2010-08-01)

A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells
by: Alessandro Cutarelli, et al.
Published: (2021-05-01)

Induced pluripotent stem cell lines from Huntington's disease mice undergo neuronal differentiation while showing alterations in the lysosomal pathway
by: Valentina Castiglioni, et al.
Published: (2012-04-01)

The Role of E3s in Regulating Pluripotency of Embryonic Stem Cells and Induced Pluripotent Stem Cells
by: Yahong Wu, et al.
Published: (2021-01-01)

Increased Ca2+ signaling in NRXN1α +/− neurons derived from ASD induced pluripotent stem cells
by: Sahar Avazzadeh, et al.
Published: (2019-12-01)

Erratum: Systemic administration of valproic acid and zonisamide promotes differentiation of induced pluripotent stem cell–derived dopaminergic neurons.
by: Tatsuya eYoshikawa, et al.
Published: (2013-07-01)

The combination of induced pluripotent stem cells and bioscaffolds holds promise for spinal cord regeneration
by: Ashley DeBrot, et al.
Published: (2018-01-01)

The Promise and Challenge of Induced Pluripotent Stem Cells for Cardiovascular Applications
by: Amr A. Youssef, MD, PhD, et al.
Published: (2016-10-01)

Rett Syndrome Induced Pluripotent Stem Cell-derived Neurons Exhibit Electrophysiological Aberrations
by: Farra, Natalie
Published: (2012)

Rett Syndrome Induced Pluripotent Stem Cell-derived Neurons Exhibit Electrophysiological Aberrations
by: Farra, Natalie
Published: (2012)

Rapid generation of regionally specified CNS neurons by sequential patterning and conversion of human induced pluripotent stem cells
by: Muwan Chen, et al.
Published: (2020-10-01)

Maturation of Human Pluripotent Stem Cell-Derived Cerebellar Neurons in the Absence of Co-culture
by: Teresa P. Silva, et al.
Published: (2020-02-01)

A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer’s Disease and Frontotemporal Dementia Disease Modeling
by: Sonia Sanz Muñoz, et al.
Published: (2020-09-01)

Induced Pluripotent Stem Cells (iPSCs)—Roles in Regenerative Therapies, Disease Modelling and Drug Screening
by: Mourad A. M. Aboul-Soud, et al.
Published: (2021-09-01)

Modeling chemotherapy induced neurotoxicity with human induced pluripotent stem cell (iPSC) -derived sensory neurons
by: Christian Schinke, et al.
Published: (2021-07-01)

Progress of Induced Pluripotent Stem Cell Technologies to Understand Genetic Epilepsy
by: Bruno Sterlini, et al.
Published: (2020-01-01)

Patient-Derived Induced Pluripotent Stem Cells (iPSCs) and Cerebral Organoids for Drug Screening and Development in Autism Spectrum Disorder: Opportunities and Challenges
by: Chiara Villa, et al.
Published: (2021-02-01)

nduced pluripotent stem cells and cell therapy
by: Banu İskender, et al.
Published: (2013-12-01)

Dataset for: Modeling chemotherapy induced neurotoxicity with human induced pluripotent stem cell (iPSC)-derived sensory neurons
by: Christian Schinke, et al.
Published: (2021-10-01)