Neurons Derived From Patient-Specific Induced Pluripotent Stem Cells: a Promising Strategy Towards Developing Novel Pharmacotherapies for Autism Spectrum Disorders

by Ryan Mokhtari, Herbert M. Lachman
Published 2016-07-01

Characterization of human pseudogene-derived non-coding RNAs for functional potential.

by Xingyi Guo, Mingyan Lin, Shira Rockowitz, Herbert M Lachman, Deyou Zheng
Published 2014-01-01

Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis

by Dejian Zhao, Mingyan Lin, Erika Pedrosa, Herbert M. Lachman, Deyou Zheng
Published 2017-11-01

Allele-biased expression in differentiating human neurons: implications for neuropsychiatric disorders.

by Mingyan Lin, Anastasia Hrabovsky, Erika Pedrosa, Tao Wang, Deyou Zheng, Herbert M Lachman
Published 2012-01-01

Heat shock alters the expression of schizophrenia and autism candidate genes in an induced pluripotent stem cell model of the human telencephalon.

by Mingyan Lin, Dejian Zhao, Anastasia Hrabovsky, Erika Pedrosa, Deyou Zheng, Herbert M Lachman
Published 2014-01-01

Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells

by Jesse Barnes, Franklin Salas, Ryan Mokhtari, Hedwig Dolstra, Erika Pedrosa, Herbert M. Lachman
Published 2018-08-01

Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stress

by Dejian Zhao, Ryan Mokhtari, Erika Pedrosa, Rayna Birnbaum, Deyou Zheng, Herbert M. Lachman
Published 2017-03-01

RNA-Seq of human neurons derived from iPS cells reveals candidate long non-coding RNAs involved in neurogenesis and neuropsychiatric disorders.

by Mingyan Lin, Erika Pedrosa, Abhishek Shah, Anastasia Hrabovsky, Shahina Maqbool, Deyou Zheng, Herbert M Lachman
Published 2011-01-01

Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks.

by Rebecca A Nebel, Dejian Zhao, Erika Pedrosa, Jill Kirschen, Herbert M Lachman, Deyou Zheng, Brett S Abrahams
Published 2016-01-01

ZNF804A Transcriptional Networks in Differentiating Neurons Derived from Induced Pluripotent Stem Cells of Human Origin.

by Jian Chen, Mingyan Lin, Anastasia Hrabovsky, Erika Pedrosa, Jason Dean, Swati Jain, Deyou Zheng, Herbert M Lachman
Published 2015-01-01

Transcriptome analysis of neural progenitor cells derived from Lowe syndrome induced pluripotent stem cells: identification of candidate genes for the neurodevelopmental and eye ma...

by Hequn Liu, Jesse Barnes, Erika Pedrosa, Nathaniel S. Herman, Franklin Salas, Ping Wang, Deyou Zheng, Herbert M. Lachman
Published 2020-05-01

MicroRNA Profiling of Neurons Generated Using Induced Pluripotent Stem Cells Derived from Patients with Schizophrenia and Schizoaffective Disorder, and 22q11.2 Del.

by Dejian Zhao, Mingyan Lin, Jian Chen, Erika Pedrosa, Anastasia Hrabovsky, H Matthew Fourcade, Deyou Zheng, Herbert M Lachman
Published 2015-01-01

Transcriptome comparison of human neurons generated using induced pluripotent stem cells derived from dental pulp and skin fibroblasts.

by Jian Chen, Mingyan Lin, John J Foxe, Erika Pedrosa, Anastasia Hrabovsky, Reed Carroll, Deyou Zheng, Herbert M Lachman
Published 2013-01-01

Patch-clamp recordings and calcium imaging followed by single-cell PCR reveal the developmental profile of 13 genes in iPSC-derived human neurons

by Glenn S. Belinsky, Matthew T. Rich, Carissa L. Sirois, Shaina M. Short, Erika Pedrosa, Herbert M. Lachman, Srdjan D. Antic
Published 2014-01-01

Comparison of REST cistromes across human cell types reveals common and context-specific functions.

by Shira Rockowitz, Wen-Hui Lien, Erika Pedrosa, Gang Wei, Mingyan Lin, Keji Zhao, Herbert M Lachman, Elaine Fuchs, Deyou Zheng
Published 2014-06-01