Prospects and limitations of antibody-mediated clearing of lipoproteins from blood plasma prior to nanoparticle tracking analysis of extracellular vesicles

Prospects and limitations of antibody-mediated clearing of lipoproteins from blood plasma prior to nanoparticle tracking analysis of extracellular vesicles

Introduction: Nanoparticle tracking analysis (NTA) enables measurement of extracellular vesicles (EVs) but lacks the ability to distinct between EVs and lipoproteins which are abundantly present in blood plasma. Limitations in ultracentrifugation and size exclusion chromatography applied for EV isol...

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Bibliographic Details
Main Authors: Morten Mørk, Aase Handberg, Shona Pedersen, Malene M. Jørgensen, Rikke Bæk, Morten K. Nielsen, Søren R. Kristensen
Format: Article
Language:English
Published: Taylor & Francis Group 2017-12-01
Series:Journal of Extracellular Vesicles
Subjects:
Nanoparticle tracking analysis
extracellular vesicle array
magnetic beads
extracellular vesicle purification
interference
very low density lipoproteins
low density lipoproteins
chylomicrons
apolipoprotein B
Online Access:http://dx.doi.org/10.1080/20013078.2017.1308779

Internet

http://dx.doi.org/10.1080/20013078.2017.1308779

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