Relationship between chromosomal aberrations and gene expressions in the p53 pathway in chronic lymphocytic leukemia

Relationship between chromosomal aberrations and gene expressions in the p53 pathway in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is a neoplasm characterized by excessive accumulation of B lymphocytes in the peripheral blood, bone marrow and lymph nodes. We assessed the expressions of 22 genes in the p53 pathway in 30 CLL patients and 15 healthy subjects by a RT2 Profiler PCR (polymerase chai...

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Bibliographic Details
Main Authors: Öztan G, Aktan M, Palanduz S, İşsever H, Öztürk S, Nikerel E, Uçur A, Bağatir G, Bayrak A, Çefle K
Format: Article
Language:English
Published: Sciendo 2020-08-01
Series:Balkan Journal of Medical Genetics
Subjects:
chronic lymphocytic leukemia (cll)
gene expression
p53 pathway
prognosis
rt2 profiler pcr (polymerase chain reaction)array
Online Access:https://doi.org/10.2478/bjmg-2020-0007

Internet

https://doi.org/10.2478/bjmg-2020-0007

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