In situ measurement of ECM rheology and microheterogeneity in embedded and overlaid 3D pancreatic tumor stroma co-cultures via passive particle tracking

In situ measurement of ECM rheology and microheterogeneity in embedded and overlaid 3D pancreatic tumor stroma co-cultures via passive particle tracking

Tumor growth is regulated by a diverse set of extracellular influences, including paracrine crosstalk with stromal partners, and biophysical interactions with surrounding cells and tissues.Studies elucidating the role of physical force and the mechanical properties of the extracellular matrix (ECM)...

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Bibliographic Details
Main Authors: Dustin P. Jones, William Hanna, Gwendolyn M. Cramer, Jonathan P. Celli
Format: Article
Language:English
Published: World Scientific Publishing 2017-11-01
Series:Journal of Innovative Optical Health Sciences
Subjects:
Microrheology
3D tumor models
matrix remodeling
mechanobiology
stromal depletion
Online Access:http://www.worldscientific.com/doi/pdf/10.1142/S1793545817420032

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http://www.worldscientific.com/doi/pdf/10.1142/S1793545817420032

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