Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance.

<h4>Background</h4>It has been proposed that muscle insulin resistance in type 2 diabetes is due to a selective decrease in the components of the mitochondrial electron transport chain and results from accumulation of toxic products of incomplete fat oxidation. The purpose of the present...

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Bibliographic Details
Main Authors: Dong-Ho Han, Chad R Hancock, Su Ryun Jung, Kazuhiko Higashida, Sang Hyun Kim, John O Holloszy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21589859/?tool=EBI