Involvement of Potassium Channels in Vasorelaxant Effect Induced by Valeriana prionophylla Standl. in Rat Mesenteric Artery

Involvement of Potassium Channels in Vasorelaxant Effect Induced by Valeriana prionophylla Standl. in Rat Mesenteric Artery

Assays in vitro and in vivo were performed on extract from roots and leaves from the Valeriana prionophylla Standl. (VPR and VPF, resp.). In phenylephrine (1 μM) precontracted rings, VPR (0.01–300 μg/mL) induced a concentration-dependent relaxation (maximum response (MR) = 75.4 ± 4.0%, EC50 = 5.97 (...

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Bibliographic Details
Main Authors: Milena Ramos Reis, Abrahão Alves de Oliveira Filho, Lilia Simone Urzedo Rodrigues, Jaíse Paiva Araújo, Priscilla Maria Pereira Maciel, Jamile Morais de Albuquerque, Valdir Cehinel Filho, Armando Cáceres, Josmara Bartolomei Fregoneze, Isac Almeida de Medeiros, Darizy Flávia Silva
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2013/147670

Internet

http://dx.doi.org/10.1155/2013/147670

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