GPIHBP1, a GPI-anchored protein required for the lipolytic processing of triglyceride-rich lipoproteins

GPIHBP1, a GPI-anchored protein required for the lipolytic processing of triglyceride-rich lipoproteins

GPIHBP1, a small glycosylphosphatidylinositol-anchored glycoprotein, is required for the lipolytic processing of triglyceride-rich lipoproteins. GPIHBP1 knockout mice exhibit chylomicronemia, even on a low-fat diet, with plasma triglyceride levels of 3,500–5,000 mg/dl. GPIHBP1 is expressed highly in...

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Bibliographic Details
Main Authors: Anne P. Beigneux, Brandon S.J. Davies, André Bensadoun, Loren G. Fong, Stephen G. Young
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Lipid Research
Subjects:
chylomicrons
lipoprotein lipase
endothelial
PPARγ
glycosylphosphatidylinositol
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520305873

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http://www.sciencedirect.com/science/article/pii/S0022227520305873

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