Calcium gluconate in phosphate buffered saline increases gene delivery with adenovirus type 5.

<h4>Background</h4>Adenoviruses are attractive vectors for gene therapy because of their stability in vivo and the possibility of production at high titers. Despite exciting preclinical data with various approaches, there are only a few examples of clear efficacy in clinical trials. Effe...

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Bibliographic Details
Main Authors: Marko T Ahonen, Iulia Diaconu, Sari Pesonen, Anna Kanerva, Marc Baumann, Suvi T Parviainen, Brad Spiller, Vincenzo Cerullo, Akseli Hemminki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20927353/?tool=EBI