Transcriptomic Identification and Biochemical Characterization of HmpA, a Nitric Oxide Dioxygenase, Essential for Pathogenesis of Vibrio vulnificus

Transcriptomic Identification and Biochemical Characterization of HmpA, a Nitric Oxide Dioxygenase, Essential for Pathogenesis of Vibrio vulnificus

Nitric oxide (NO) and its derivatives are important effectors of host innate immunity, disrupting cellular function of infecting pathogens. Transcriptome analysis of Vibrio vulnificus, an opportunistic human pathogen, identified a set of genes induced upon exposure to NO. Among them, VvhmpA (V. vuln...

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Bibliographic Details
Main Authors: Dukyun Kim, Eun Jung Na, Suhyeon Kim, Jung Sung Kim, Young Hyun Jung, Jiafu Cao, Ho Jae Han, Iel Soo Bang, Jin-Wook Yoo, Nam-Chul Ha, Sang Ho Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
Vibrio vulnificus
microbiology
nitric oxide dioxygenase
flavohemoglobins
virulence factors
gene expression profiling
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02208/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.02208/full

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