The Influence of Standardized Valeriana officinalis Extract on the CYP3A1 Gene Expression by Nuclear Receptors in In Vivo Model

Valeriana officinalis is one of the most popular medicinal plants commonly used as a sedative and sleep aid. It is suggested that its pharmacologically active compounds derived from the root may modulate the CYP3A4 gene expression by activation of pregnane X receptor (PXR) or constitutive androstane...

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Main Authors: Anna Bogacz, Przemyslaw M. Mrozikiewicz, Monika Karasiewicz, Joanna Bartkowiak-Wieczorek, Marian Majchrzycki, Przemyslaw L. Mikolajczak, Marcin Ozarowski, Edmund Grzeskowiak
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/819093