In Vitro Cell Culture Infectivity Assay for Human Noroviruses

In Vitro Cell Culture Infectivity Assay for Human Noroviruses

Human noroviruses cause severe, self-limiting gastroenteritis that typically lasts 24–48 hours. Because of the lack of suitable tissue culture or animal models, the true nature of norovirus pathogenesis remains unknown. We show that noroviruses can infect and replicate in a 3-dimensional (3-D), orga...

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Bibliographic Details
Main Authors: Timothy M. Straub, Kerstin Höner zu Bentrup, Patricia Orosz Coghlan, Alice Dohnalkova, Brooke K. Mayer, Rachel A. Bartholomew, Catherine O. Valdez, Cynthia J. Bruckner-Lea, Charles P. Gerba, Morteza A. Abbaszadegan, Cheryl A. Nickerson
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2007-03-01
Series:Emerging Infectious Diseases
Subjects:
norovirus
cytopathic effect
fluorescence
electron microscopy
3-dimensional cell culture
organoids
Online Access:https://wwwnc.cdc.gov/eid/article/13/3/06-0549_article

Internet

https://wwwnc.cdc.gov/eid/article/13/3/06-0549_article

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