Chemokine coreceptor signaling in HIV-1 infection and pathogenesis.
Binding of the HIV-1 envelope to its chemokine coreceptors mediates two major biological events: membrane fusion and signaling transduction. The fusion process has been well studied, yet the role of chemokine coreceptor signaling in viral infection has remained elusive through the past decade. With...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-12-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2790611?pdf=render |