c-Src-dependent EGF receptor transactivation contributes to ET-1-induced COX-2 expression in brain microvascular endothelial cells
<p>Abstract</p> <p>Background</p> <p>Endothelin-1 (ET-1) is elevated and participates in the regulation of several brain inflammatory disorders. The deleterious effects of ET-1 on endothelial cells may aggravate brain inflammation mediated through the upregulation of cy...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-07-01
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Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/9/1/152 |