Metabolic control analysis of respiration in human cancer tissue

Metabolic control analysis of respiration in human cancer tissue

Bioenergetic profiling of cancer cells is of great potential because it can bring forward new and effective therapeutic strategies along with early diagnosis. Metabolic Control Analysis (MCA) is a methodology that enables quantification of the flux control exerted by different enzymatic steps in a m...

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Bibliographic Details
Main Authors: Tuuli eKaambre, Vladimir eChekulayev, Igor eShevchuk, Kersti eTepp, Natalja eTimohhina, Minna eVarikmaa, Rafaela eBagur, Aleksandr eKlepinin, Tiia eAnmann, Andre eKoit, Andrus eKaldma, Rita eGuzun, Vahur eValvere, Valdur eSaks
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Physiology
Subjects:
breast cancer
colorectal cancer
respiratory chain
Metabolic Control Analysis
Warburg effect
OxPhos
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00151/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00151/full

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