Raised Plasma Neurofilament Light Protein Levels After Rewarming Are Associated With Adverse Neurodevelopmental Outcomes in Newborns After Therapeutic Hypothermia

Raised Plasma Neurofilament Light Protein Levels After Rewarming Are Associated With Adverse Neurodevelopmental Outcomes in Newborns After Therapeutic Hypothermia

Aim: To determine the predictive value of plasma neurofilament light protein (NfL) as a prognostic marker for outcomes in babies who have undergone therapeutic hypothermia (TH) for hypoxic ischemic encephalopathy (HIE).Method: NfL levels from three groups of term newborns were compared: (1) those wi...

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Bibliographic Details
Main Authors: Divyen K. Shah, Ping K. Yip, Akif Barlas, Pavithira Tharmapoopathy, Vennila Ponnusamy, Adina T. Michael-Titus, Philippa Chisholm
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neurology
Subjects:
newborn
hypoxic-ischemic encephalopathy
neurodevelopment
neurofilament light protein
therapautic hypothermia
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.562510/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2020.562510/full

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