Impact of an additional chronic BDNF reduction on learning performance in an Alzheimer mouse model

Impact of an additional chronic BDNF reduction on learning performance in an Alzheimer mouse model

There is increasing evidence that brain-derived neurotrophic factor (BDNF) plays a crucial role in AD pathology. A number of studies demonstrated that AD patients exhibit reduced BDNF levels in the brain and the blood serum, and in addition, several animal-based studies indicated a potential protect...

Full description

Bibliographic Details
Main Authors: Laura ePsotta, Carolin eRockahr, Michael eGruss, Elmar eKirches, Katharina A Braun, Volkmar eLessmann, Joerg eBock, Thomas eEndres
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
BDNF
object recognition
Alzheimer’s disease
water maze
active avoidance
APP/Ps1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00058/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00058/full

Similar Items