The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure.

The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure.

BACKGROUND: CCL19 and CCL21, acting through CCR7, are termed homeostatic chemokines. Based on their role in concerting immunological responses and their proposed involvement in tissue remodeling, we hypothesized that these chemokines could play a pathogenic role in heart failure (HF). METHODOLOGY/PR...

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Bibliographic Details
Main Authors: Arne Yndestad, Alexandra Vanessa Finsen, Thor Ueland, Cathrine Husberg, Christen P Dahl, Erik Øie, Leif Erik Vinge, Ivar Sjaastad, Øystein Sandanger, Trine Ranheim, Kenneth Dickstein, John Kjekshus, Jan Kristian Damås, Arnt E Fiane, Denise Hilfiker-Kleiner, Martin Lipp, Lars Gullestad, Geir Christensen, Pål Aukrust
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3299722?pdf=render

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http://europepmc.org/articles/PMC3299722?pdf=render

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