Methylene Blue Induces Macroautophagy through 5' Adenosine Monophosphate-Activated Protein Kinase Pathway to Protect Neurons from Serum Deprivation

Methylene Blue Induces Macroautophagy through 5' Adenosine Monophosphate-Activated Protein Kinase Pathway to Protect Neurons from Serum Deprivation

Methylene blue has been shown to be neuroprotective in multiple experimental neurodegenerative disease models. However, the mechanisms underlying the neuroprotective effects have not been fully elucidated. Previous studies have shown that macroautophagy has multiple beneficial roles for maintaining...

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Bibliographic Details
Main Authors: Luokun eXie, Wenjun eLi, Ali eWinters, Fang eYuan, Kunlin eJin, Shaohua eYang
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Alzheimer Disease
Methylene Blue
Neuroprotection
AMPK
Macroautophagy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00056/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00056/full

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